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Allele : Tg(ACTB-Wld)#Cole transgene insertion, Michael Coleman

Primary Identifier  MGI:5911098 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(ACTB-Wld)#Cole
Strain of Origin  (C57BL/6 x CBA)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  A construct consisting of the human beta actin promoter followed by the cDNA for Wlds that is an in-frame fusion of exon 1 and 2 of Ube4b to exon 2 onwards of Nmnat1, was injected into the pronuclei of fertilized (C57BL/6 x CBA)F1 eggs that do not express Wlds. Four lines were established (4830, 4836, 4839 and 4858) and expression levels of this transgene varied from considerably lower than to similar to that of Wlds in the C57Bl/6Ola strain.
  • mutations:
  • Insertion
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories