Primary Identifier | MGI:5909274 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(TCRAMS2-3C8,TCRBMS2-3C8)#Kito |
Strain of Origin | C57BL/6 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The transgene contains rearranged MS2-3C8 TCR Valpha (AV4S1AJ32) and Vbeta (BV2S1BJ1S6) chains from the T cell clone MS2-3C8 isolated from the peripheral blood of a patient with relapsing/remitting multiple sclerosis, which recognizes the human MBP 111-129 epitope. Lines B6 and G2 were generated. The pound symbol is used when no line is specified and/or lines are pooled. |