Primary Identifier | MGI:5909287 | Allele Type | Transgenic |
Attribute String | Recombinase | Gene | Tg(Stab2-icre)1.2Cger |
Strain of Origin | C57BL/6NCrl | Is Recombinase | true |
Is Wild Type | false |
molecularNote | A cDNA containing a codon improved version of cre recombinase followed by polyA signal sequence was fused into BAC clone at exon 1 of mouse Stab2 gene so that cre expression is driven by the regulatory sequences of the BAC gene. The resulting modified BAC was used to generate this transgene. Three founder lines 1.1, 1.2, and 1.3 were identified. The line 1.2 displaying cre activity in liver sinusoidal endothelial cells were used for the study. |