Primary Identifier | MGI:5911243 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(TLR4)5271Haj |
Strain of Origin | C3H or C57BL/6 | Is Recombinase | false |
Is Wild Type | false |
description | BAC DNA was microinjected into (C57BL/6 x C3H)F1 x C57BL/6 (B6C3 x C57BL/6) fertilized oocytes. (J:194866) |
molecularNote | The transgene was designed with a human bacterial artificial chromosome (BAC) RP11-150L1 containing the entire human TLR4 gene. Founder line 5271 was established and carries two copies of the transgene. The BAC contains at least 50 Kb of human genomic sequences flanking the TLR4 gene. |