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Allele : Tg(TLR4)5271Haj transgene insertion 5271, Adeline Hajjar

Primary Identifier  MGI:5911243 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(TLR4)5271Haj
Strain of Origin  C3H or C57BL/6 Is Recombinase  false
Is Wild Type  false
description  BAC DNA was microinjected into (C57BL/6 x C3H)F1 x C57BL/6 (B6C3 x C57BL/6) fertilized oocytes. (J:194866)
molecularNote  The transgene was designed with a human bacterial artificial chromosome (BAC) RP11-150L1 containing the entire human TLR4 gene. Founder line 5271 was established and carries two copies of the transgene. The BAC contains at least 50 Kb of human genomic sequences flanking the TLR4 gene.
  • mutations:
  • Insertion
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories