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Allele : Tg(Myh6-ACTC1*E361G)361.20Sbm transgene insertion 361.20, Steven B Marston
Primary Identifier  MGI:5906238 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(Myh6-ACTC1*E361G)361.20Sbm
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  The heart restricted murine alpha-myosin heavy chain promoter drives the expression of human cardiac actin with a glycine substitution for glutamic acid at amino acid 361 (E361G). This is a dominant negative mutation. Two lines were established: 361.20 and 361.13. Mice express this mutation at around 50% of total actin in the heart.
  • mutations:
  • Insertion
  • synonyms:
  • ACTC E361G,
  • ACTC E361G
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories





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