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Allele : Tg(Myh6-Snai1)B10Jcc transgene insertion B10, James C Cross

Primary Identifier	MGI:5906252	Allele Type	Transgenic
Attribute String	Inserted expressed sequence	Gene	Tg(Myh6-Snai1)B10Jcc
Strain of Origin	Not Specified	Is Recombinase	false
Is Wild Type	false

molecularNote

The mouse Snai1 cDNA is under the control of the cardiac specific mouse myosin heavy chain alpha promoter. Three lines were established: B10, B18 and B26. Founder lines B18 and B26 died from cardiac failure while B10 survived. This line has a copy number of 2.

mutations:
Insertion

synonyms:
MHC-Snail,
MHC-Snail

earliestPublication:
Hesse M, et al. (2007) Dilated cardiomyopathy is associated with reduced expression of the cardiac sodium channel Scn5a. Cardiovasc Res 75(3):498-509

1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

4 Publication categories

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