| Primary Identifier | MGI:6117098 | Allele Type | Endonuclease-mediated |
| Attribute String | Modified isoform(s) | Gene | Actb |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | CRISPR/Cas9-mediated gene editing was used to introduce five point mutations into the native mouse beta-actin gene, altering it to encode gamma-actin protein. In homozygous mice, no beta-actin protein is produced, and gamma-actin is expressed under the control of the endogenous beta-actin promoter. |
