| Primary Identifier | MGI:6121070 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Dstyk |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site was inserted into intron 3 and an FRT site flanked neomycin resistance gene cassette and a second loxP site into intron 13. The neo cassette was removed through subsequent flp-mediated recombination. Exons 4-13 were deleted through subsequent cre-mediated recombination. Exons 8-13 code for the kinase domain. qRT-PCR and western blots confirmed the absence of expression from this allele. |
