| Primary Identifier | MGI:6117093 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Cspp1 |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by injecting Cas9 RNA and 4 guide sequences CTATTGGGCCAGGAGGCTAG, GAGTTACTATTAAGTACACT, TGTTGCCTAATTGTGATTGG and TGAGTCTTACATATGGCAAT, which resulted in a 592 bp deletion beginning at Chromosome 1 positive strand position 10,047,149 bp and ending after 10,047,740 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001255443 (exon 3) and 489 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 33 and early truncation 5 amino acids later. |
