| Help | About | Contact Us

Allele : Upf3a<tm1.1Wilk> UPF3 regulator of nonsense transcripts homolog A (yeast); targeted mutation 1.1, Miles F Wilkinson

Primary Identifier	MGI:6117429	Allele Type	Targeted
Attribute String	Conditional ready, No functional change	Gene	Upf3a
Transmission	Germline	Strain of Origin	129
Is Recombinase	false	Is Wild Type	false

molecularNote

A loxP site was inserted upstream of exon 3 and an FRT flanked neomycin resistance gene cassette and loxP site were inserted downstream of exon 3. Flpe-mediated recombination removed the neomycin cassette.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
Upf3a<fl>,
Upf3a<fl>

earliestPublication:
Shum EY, et al. (2016) The Antagonistic Gene Paralogs Upf3a and Upf3b Govern Nonsense-Mediated RNA Decay. Cell 165(2):382-95

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

4 Publication categories

Questions? Comments? Click here!

MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Your name:
Your email address:
Subject:
Message:	---- Current page: ---- /mousemine/report.do?id=76609001

MouseMine