Primary Identifier | MGI:6116854 | Allele Type | Targeted |
Attribute String | Recombinase | Gene | Crh |
Transmission | Germline | Strain of Origin | (129S6/SvEvTac x C57BL/6J)F1 |
Is Recombinase | true | Is Wild Type | false |
molecularNote | The coding sequences for an an internal ribosomal entry site (IRES) followed by an optimized FLP recombinase and a self-excising lox2372-flanked neomycin-Ace-cre cassette are introduced immediately after the Stop codon. In situ characterization demonstrates that flpo and Crh expression completely overlap in the pontine micturition center (PMC) in the pons. |