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Allele : Crh<tm1.1(flpo)Bsab> corticotropin releasing hormone; targeted mutation 1.1, Bernardo Sabatini

Primary Identifier  MGI:6116854 Allele Type  Targeted
Attribute String  Recombinase Gene  Crh
Transmission  Germline Strain of Origin  (129S6/SvEvTac x C57BL/6J)F1
Is Recombinase  true Is Wild Type  false
molecularNote  The coding sequences for an an internal ribosomal entry site (IRES) followed by an optimized FLP recombinase and a self-excising lox2372-flanked neomycin-Ace-cre cassette are introduced immediately after the Stop codon. In situ characterization demonstrates that flpo and Crh expression completely overlap in the pontine micturition center (PMC) in the pons.
  • mutations:
  • Insertion
  • synonyms:
  • Crh-ires-FlpO,
  • Crh-ires-FlpO
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

1 Driven By

8 Publication categories