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Allele : Clpp<tm1.2Arte> caseinolytic mitochondrial matrix peptidase proteolytic subunit; targeted mutation 1.2, TaconicArtemis

Primary Identifier  MGI:6117346 Allele Type  Targeted
Attribute String  Null/knockout Gene  Clpp
Transmission  Germline Strain of Origin  C57BL/6NTac
Is Recombinase  false Is Wild Type  false
molecularNote  LoxP sites flank exons 3-5 and a puromycin resistance cassette flanked by FRT sites was inserted into intron 5. Flp-mediated recombination removed the puromycin selection marker. Cre-mediated recombination removed exons 3-5, removing a part of the protease domain and generated a frameshift from exons 2 to 6.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories