|  Help  |  About  |  Contact Us

Allele : Phf8<tm1.1Hoch> PHD finger protein 8; targeted mutation 1.1, Konrad Hochedlinger

Primary Identifier  MGI:6094243 Allele Type  Targeted
Attribute String  Null/knockout Gene  Phf8
Transmission  Germline Strain of Origin  (C57BL/6 x 129S4/SvJae)F1
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted into intron 6 and a neomycin resistance gene cassette and a second loxP site into intron 8. Exons 7 and 8 (and the neo cassette) were subsequently deleted through cre-mediated recombination, resulting in a null allele. Western blots confirmed the loss of protein expression from this allele and RNA-seq confirmed the lack of exon 7 and 8 reads.
  • mutations:
  • Insertion,
  • Intragenic deletion
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories