| Primary Identifier | MGI:6094267 | Allele Type | Transgenic |
| Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(TLR4*D299G*T399I)8Haj |
| Strain of Origin | C57BL/6 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The transgene was generated with a modified version of human genomic BAC RP11-150L1. Using recombineering, A>G and C>T substitutions were introduced that resulted in D299G (p.Asp299Gly) and T399I (p.Thr399Ile) mutations in the translated petide, respectively. The copy number of this allele, as determined by RT-PCR, is 8. |
