Primary Identifier | MGI:6095627 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Sphk1 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
description | Originally published in Pushparaj PN et al. "Sphingosine kinase1 is pivotal for Fc{epsilon}RI-mediated mast cell signaling and functional responses in vitro and in vivo" (J Immunol. 2012 Sep 15;189(6):3262) but later retracted (see retraction PMID: 22956763 for more detail). The retraction did not impact the generation of the alleles performed by Genoway. |
molecularNote | A neomycin resistance cassette replaced exons 3 through 6. |