| Primary Identifier | MGI:5927688 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Pias3 |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site was inserted into intron 1 and a second loxP site and an FRT site flanked neomycin resistance gene cassette into intron 5. The neo cassette was removed through subsequent flp-mediated recombination. Exons 2-5 were deleted through cre-mediated recombination by crossing these mice with mice carrying the Tg(rx3-icre)1Mjam allele. That allele shows leaky expression in the oocytes, thus creating some non-conditional null mouse lines i this crossing. |
