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Allele : Impg1<em1(IMPC)J> interphotoreceptor matrix proteoglycan 1; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:5927700 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Impg1
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by injecting Cas9 RNA and 4 guide sequences TCAATATCCTAGGAGCAGCA, CCTTAGTAACCATTTCAAAG, TTAAAGTTAGCCATGCAAAA and ATTAGTGTGTGAACATAAGC, which resulted in a 312 bp deletion beginning at Chromosome 9 negative strand position 80,435,559 bp and ending after 80,435,248 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000694908 (exon 3) and 145 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 99 and early truncation 12 amino acids later.
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories