| Primary Identifier | MGI:6095171 | Allele Type | Transgenic |
| Attribute String | Conditional ready, Constitutively active, Inserted expressed sequence, Modified isoform(s), Reporter | Gene | Tg(Actb-Nfe2l2,-EGFP)CMVSwnr |
| Strain of Origin | FVB/N | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The transgene is derived from the Tg(CMV-SALL4_iB)#Chai allele and comprises the following elements: the CMV early enhancer a beta-actin promoter, a loxP site flanked STOP cassette, the cDNA for the constitutively active isoform of the mouse Nfe2l2 gene which lacks sequence for the N-terminal Neh2 domain, an internal ribosomal entry site (IRES), and the EGFP fluorescent reporter gene. The construct was injected into the proneclei of FVB/N fertilized oocytes. The mouse gene (and the reporter) will only be expressed after deletion of the STOP cassette through Cre-mediated recombination. |
