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Allele : Phox2a<tm1(Asci2*)Jbr> paired-like homeobox 2a; targeted mutation 1, Jean-Francois Brunet

Primary Identifier  MGI:6111410 Allele Type  Targeted
Attribute String  Inserted expressed sequence Gene  Phox2a
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A cDNA for rat Asic2 harboring a G430F mutation was inserted between the first and second exon of the gene, preceded by a floxed EGFP-Neo-STOP-IRES cassette, itself preceded by a splice acceptor site. Upon Cre-mediated recombination the mutant rat Asic2, encoding a toxic allele of the sodium channel, is transcribed from the endogenous promoter.
  • mutations:
  • Insertion
  • synonyms:
  • Phox2a<ASIC2a>,
  • Phox2a<ASIC2a>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories

Trail: Allele