Primary Identifier | MGI:6098741 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(CD3E)31Alat |
Strain of Origin | (C57BL/6 x DBA/2)F2 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Human cosmid cEpsilon1, containing the CD3E gene, was injected into BDF2 fertilized oocytes. Five independent lines were established: three low copy and two high copy number. This allele represents a high copy number with approximately 90 transgene insertions. Northern blot analysis showed that the human gene was expressed in the correct T cell-specific manner. |