| Primary Identifier | MGI:6158660 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Nr3c1 |
| Transmission | Germline | Strain of Origin | 129 and C57BL/6 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A targeting vector was designed to insert a loxP site upstream of exon 3 and a second loxP site downstream of exon 3, followed by a frt-flanked neomycin resistance (neo) cassette. Flp-mediated recombination remvoed the neo cassette. Resulting parental mice with allele Nr3c1tm1.1Jda were crossed with actin-cre mice to delete exon 3. Mice were backcrossed to breeding out the cre transgene. |
