| Primary Identifier | MGI:6112025 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Sccpdh |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by injecting Cas9 RNA and 4 guide sequences CTATAGGCAGGTGATCTAGG, TATCTGACCCAATTATAGAG, ACATTAGAGAGGGGGACACA and GTTTGTTCTGATACAAAGAA, which resulted in a 576 bp deletion beginning at Chromosome 1 positive strand position 179,670,350 bp and ending after 179,670,925 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001069513 (exon 2) and 463 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 63 and early truncation 13 amino acids later. |
