Primary Identifier | MGI:6103872 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(Myh6-CRYAB*R120G)7302Ijb |
Strain of Origin | Not Specified | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The mouse alpha-myosin heavy chain promoter drives the expression of the human alphaB-crystallin with the missense R120G mutation. Two lines were established: 7302 and 7313. Total Cryab protein, both endogenous and transgene expression, is increased 6-fold in this line. |