Primary Identifier | MGI:6107852 | Allele Type | Targeted |
Attribute String | Not Specified | Gene | Bag3 |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Codon 455 GAA encoding glutamic acid in exon 4 was changed to AAA encoding lysine (E455K) and a FRT site flanked neomycin selection cassette was inserted upstream of this mutation. Flp-mediated recombination removed the neomycin cassette. This mutation is equivalent to the human E455K mutation. |