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Allele : Myh10<ehc> myosin, heavy polypeptide 10, non-muscle; embryonic hydrocephalus and cardiac defects

Primary Identifier  MGI:6108305 Allele Type  Chemically induced (ENU)
Attribute String  Null/knockout Gene  Myh10
Inheritance Mode  Recessive Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
description  This mutation was one of two identified in l11Jus27.
molecularNote  ENU mutagenesis induced a G to T in the splice donor site following exon 18 that results in skipping of the exon and protein truncation (1-703). THe predicted truncated protein lacks the coiled coil rod domain and undetectable on western blots with the C-terminal NMHC IIB antibody.
  • mutations:
  • Single point mutation
  • synonyms:
  • Myh10<l11Jus27.1>,
  • Myh10<l11Jus27.1>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories