Primary Identifier | MGI:6108305 | Allele Type | Chemically induced (ENU) |
Attribute String | Null/knockout | Gene | Myh10 |
Inheritance Mode | Recessive | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
description | This mutation was one of two identified in l11Jus27. |
molecularNote | ENU mutagenesis induced a G to T in the splice donor site following exon 18 that results in skipping of the exon and protein truncation (1-703). THe predicted truncated protein lacks the coiled coil rod domain and undetectable on western blots with the C-terminal NMHC IIB antibody. |