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Allele : Tg(Pcp2-ATXN1*82Q)R2Horr transgene insertion R2, Harry T Orr

Primary Identifier  MGI:6113813 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(Pcp2-ATXN1*82Q)R2Horr
Strain of Origin  FVB/N Is Recombinase  false
Is Wild Type  false
molecularNote  The transgene consists of a mouse Pcp2 promoter and a human mutant SCA1 cDNA sequence with 82 CAG repeats. The 835 bp fragment of mouse Pcp2 regulatory sequence include exon 1, intron 1, and part of exon 2 of Pcp2. The Pcp2 promoter targets transgene expression to Purkinje cells. Line R2 was generated.
  • mutations:
  • Insertion
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

1 Driven By

3 Publication categories