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Allele : Adamts18<tm1.1Cbri> ADAM metallopeptidase with thrombospondin type 1 motif 18; targeted mutation 1.1, Cathrin Brisken

Primary Identifier  MGI:6118086 Allele Type  Targeted
Attribute String  Null/knockout Gene  Adamts18
Transmission  Germline Strain of Origin  129S/SvEv
Is Recombinase  false Is Wild Type  false
molecularNote  A PGK-driven neomycin resistance gene flanked by FRT sites and followed by a loxP site were inserted 200 bp before exon 8 and another loxP site was inserted 200 bp after exon 9. Germline Cre-mediated recombination removed exons 8 and 9 and this is predicted to cause a frame shift resulting in a protein truncated at amino acid 405.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Adamts18<KO>,
  • Adamts18<KO>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele