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Allele : Map3k8<M4Btlr> mitogen-activated protein kinase kinase kinase 8; mutation 4, Bruce Beutler

Primary Identifier  MGI:6113556 Allele Type  Chemically induced (ENU)
Attribute String  Not Specified Gene  Map3k8
Inheritance Mode  Semidominant Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
Project Collection  Beutler Mutagenetix
molecularNote  ENU-induced T to A transversion at base pair 4,339,548 (v38) on chromosome 18, or base pair 13,865 in the NC_000084 GenBank genomic region. The mutation corresponds to residue 946 in the mRNA sequence NM_008713 within exon 5 of 8 total exons. The mutation results in a serine to arginine substitution at position 274 (S274R) in the protein.
  • mutations:
  • Single point mutation
  • synonyms:
  • Flojo,
  • Flojo
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories