| Primary Identifier | MGI:6113585 | Allele Type | Chemically induced (ENU) |
| Attribute String | Modified isoform(s) | Gene | Pik3r1 |
| Inheritance Mode | Other (see notes) | Strain of Origin | C57BL/6J |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | Beutler Mutagenetix |
| description | Inheritance is unknown/not applicable. |
| molecularNote | ENU-induced G to A transition at base pair 101,689,444 (v38) on chromosome 13, or base pair 78,774 in the GenBank genomic region NC_000079. The mutation corresponds to residue 1,694 in the mRNA sequence NM_001077495 within exon 9 of 16 total exons and to residue 605 in the mRNA sequence NM_001024955 within exon 3 of 10 total exons. The mutation results in an arginine to glutamine substitution at residue 358 (R358Q) in the p85alpha protein as well as an R88Q substitution in p55alpha and p50alpha. |
