|  Help  |  About  |  Contact Us

Allele : Tg(Pcp2-ATXN1*82Q*V591A*S602D)1BHorr transgene insertion 1B, Harry T Orr
Primary Identifier  MGI:6113692 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(Pcp2-ATXN1*82Q*V591A*S602D)1BHorr
Strain of Origin  FVB/N Is Recombinase  false
Is Wild Type  false
molecularNote  The transgene consists of a mouse Pcp2 promoter driving the expression of a human ATXN1 (SCA1) cDNA with 82 CAG repeats and a valine to alanine change at amino acid 591 (V591A) and serine to aspartic acid at posistion 602 (S602D). This is the high expressing line. The Pcp2 promoter targets transgene expression to Purkinje cells.
  • mutations:
  • Insertion
  • synonyms:
  • PCP2-ATXN1[82Q]V591A;S602D,
  • PCP2-ATXN1[82Q]V591A;S602D
Paste the following link
Quick Links:
SummaryGenomePhenotypeOther
 
Quick Links:
SummaryGenomePhenotypeOther
 
Lists
This Allele isn't in any lists. Upload a list.

1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

1 Driven By

Trail: Allele

3 Publication categories

Trail: Allele




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom