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Allele : Ncr1<m1J> natural cytotoxicity triggering receptor 1; mutation 1, Jackson

Primary Identifier  MGI:6117782 Allele Type  Spontaneous
Attribute String  Null/knockout Gene  Ncr1
Inheritance Mode  Recessive Strain of Origin  B6.SJL-Ptprc<a> Pepc<b>/BoyJ
Is Recombinase  false Is Wild Type  false
molecularNote  A T-to-C transition in the 40th nucleotide from the start codon c.40T>C results in a change from cysteine to arginine at amino acid 14 (p.C14R), which is in the signal peptide region and although transcript is found at normal levels the protein is absent from NK cells.
  • mutations:
  • Single point mutation
  • synonyms:
  • ziggy,
  • Ncr1<C14R>,
  • ziggy,
  • Ncr1<C14R>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories