Primary Identifier | MGI:6117782 | Allele Type | Spontaneous |
Attribute String | Null/knockout | Gene | Ncr1 |
Inheritance Mode | Recessive | Strain of Origin | B6.SJL-Ptprc<a> Pepc<b>/BoyJ |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A T-to-C transition in the 40th nucleotide from the start codon c.40T>C results in a change from cysteine to arginine at amino acid 14 (p.C14R), which is in the signal peptide region and although transcript is found at normal levels the protein is absent from NK cells. |