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Allele : Adprhl1<em1(IMPC)H> ADP-ribosylhydrolase like 1; endonuclease-mediated mutation 1, Harwell

Primary Identifier	MGI:6140149	Allele Type	Endonuclease-mediated
Attribute String	Modified isoform(s)	Gene	Adprhl1
Strain of Origin	C57BL/6NTac	Is Recombinase	false
Is Wild Type	false	Project Collection	IMPC

molecularNote

This mutation is a 1087 bp deletion that removes Adprhl1 exons 3 and 4. While the full length protein is not expressed, expression of two smaller isoforms of the gene is unaffected.

mutations:
Intragenic deletion

earliestPublication:
Smith SJ, et al. (2020) Defective heart chamber growth and myofibrillogenesis after knockout of adprhl1 gene function by targeted disruption of the ancestral catalytic active site. PLoS One 15(7):e0235433

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

2 Carried By

0 Driven By

7 Publication categories

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