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Allele : Acvr1<tm1Glh> activin A receptor, type 1; targeted mutation 1, David J Goldhamer
Primary Identifier  MGI:6140231 Allele Type  Targeted
Attribute String  Conditional ready, Reporter Gene  Acvr1
Transmission  Germline Strain of Origin  (129S6/SvEvTac x C57BL/6J)F1
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 5 was replaced with a mutated exon containing an arginine to histidine change at position 206 (R206H) in the glycine-serine-rich domain seen in patients with fibrodysplasia ossificans progressiva. A loxP-flanked CAG- tdTomato-T2A-Neo stop cassette was inserted in intron 4.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Acvr1<tnR206H>,
  • Acvr1<tnR206H>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

10 Publication categories





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