Primary Identifier | MGI:6114713 | Allele Type | Chemically induced (ENU) |
Attribute String | Not Specified | Gene | Rac2 |
Inheritance Mode | Other (see notes) | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Beutler Mutagenetix |
description | CD8+ T cell phenotype is dominant; other phenotypes are recessive. |
molecularNote | ENU-induced T to C transition at base pair 78,564,934 (v38) on chromosome 15, or base pair 7,850 in the GenBank genomic region NC_000081. The mutation corresponds to residue 515 in the mRNA sequence NM_009008 within exon 5 of 7 total exons. The mutation results in an isoleucine to threonine substitution at position 126 (I126T) in the protein. |