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Allele : Rac2<M5Btlr> Rac family small GTPase 2; mutation 5, Bruce Beutler

Primary Identifier  MGI:6114713 Allele Type  Chemically induced (ENU)
Attribute String  Not Specified Gene  Rac2
Inheritance Mode  Other (see notes) Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
Project Collection  Beutler Mutagenetix
description  CD8+ T cell phenotype is dominant; other phenotypes are recessive.
molecularNote  ENU-induced T to C transition at base pair 78,564,934 (v38) on chromosome 15, or base pair 7,850 in the GenBank genomic region NC_000081. The mutation corresponds to residue 515 in the mRNA sequence NM_009008 within exon 5 of 7 total exons. The mutation results in an isoleucine to threonine substitution at position 126 (I126T) in the protein.
  • mutations:
  • Single point mutation
  • synonyms:
  • Lamb,
  • Lamb
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele