| Primary Identifier | MGI:6114733 | Allele Type | Chemically induced (ENU) |
| Attribute String | Not Specified | Gene | Rims4 |
| Inheritance Mode | Recessive | Strain of Origin | C57BL/6J |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | Beutler Mutagenetix |
| molecularNote | ENU-induced G to A transition at base pair 163,864,865 (v38) on chromosome 2, or base pair 54,126 in the GenBank genomic region NC_000068 within the donor splice site of intron 5. The effect of the mutation at the cDNA and protein level have not examined, but the mutation is predicted to result in the use of a cryptic splice site in exon 5. The use of a cryptic splice site would result in a transcript with a 42-base pair deletion in exon 5 and an in-frame deletion of 14 amino acids (amino acids 185-198). |
