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Allele : Pik3ca<tm4Bvan> phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; targeted mutation 4, Bart Vanhaesebroeck
Primary Identifier  MGI:6115348 Allele Type  Targeted
Attribute String  Hypomorph Gene  Pik3ca
Transmission  Germline Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
molecularNote  Gene targeted produced the nucleotide substitution CAT to CGT and resulted in the amino acid substitution of arginine for histidine at position 1047 (H1047R). An FRT-flanked neomycin resistance cassette was inserted into exons 19 and 20.
  • synonyms:
  • Pik3ca<H1047R+neo>,
  • Pik3ca<H1047R+neo>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories





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