| Primary Identifier | MGI:6120493 | Allele Type | Targeted |
| Attribute String | Null/knockout, Recombinase | Gene | Tenm3 |
| Transmission | Germline | Strain of Origin | (C57BL/6 x 129S6/SvEvTac)F1 |
| Is Recombinase | true | Is Wild Type | false |
| molecularNote | Cre recombinase, a synthetic intron, woodchuck hepatitis virus post-transcriptional regulatory element (WPRE), bovine growth hormone polyA (bGH pA) and an FRT-flanked PGK-neomycin cassette replace sequences of the mouse Tenm3 gene immediately 3' of the ATG transcriptional start site in exon 1 via homologous recombination in embryonic stem cells. The neomycin cassette was retained.The mutation functions as a Tenm3 null allele lacking protein expression. |
