|  Help  |  About  |  Contact Us

Allele : Igfbp7<tm1.2Dsar> insulin-like growth factor binding protein 7; targeted mutation 1.2, Devanand Sarkar

Primary Identifier  MGI:6120545 Allele Type  Targeted
Attribute String  Null/knockout Gene  Igfbp7
Transmission  Germline Strain of Origin  (129S6/SvEvTac x C57BL/6J)F1
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP (L83) site was inserted upstream of the promoter and FRT-flanked neomycin cassette and a second loxP site were inserted downstream of intron 1. Flp-mediated recombination removed the neomycin cassette. Cre-mediated recombination removed the promoter and exon 1. Western blot analysis confirmed absence of protein in the liver, spleen, and kidney.
  • mutations:
  • Insertion,
  • Intragenic deletion
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories