| Primary Identifier | MGI:6120545 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Igfbp7 |
| Transmission | Germline | Strain of Origin | (129S6/SvEvTac x C57BL/6J)F1 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP (L83) site was inserted upstream of the promoter and FRT-flanked neomycin cassette and a second loxP site were inserted downstream of intron 1. Flp-mediated recombination removed the neomycin cassette. Cre-mediated recombination removed the promoter and exon 1. Western blot analysis confirmed absence of protein in the liver, spleen, and kidney. |