| Primary Identifier | MGI:6116519 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Adgrg7 |
| Transmission | Germline | Strain of Origin | 129/Sv |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A genomic fragment (8.4 kb) covering exons 10-12 was replaced with a 1.9-kb phosphoglycerate kinase-neomycin resistance (PGK-Neo) cassette. This mutation causes an reading frame shift and thereby generates a loss-of-function allele. Semi-quantitative RT-PCR and immunofluorescence staining confirmed absence of expression in the intestine of homozygous mutant mice. |
