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Allele : Celf1<tm1Timc> CUGBP, Elav-like family member 1; targeted mutation 1, Nikolai A Timchenko
Primary Identifier  MGI:6144284 Allele Type  Targeted
Gene  Celf1 Transmission  Germline
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  A substitution of AGT to GCG in exon 11 results in an alanine for serine substitution at amino acid 302 (S302A), resulting in an unphosphorylated (by cyclin D1/D2-cdk4) isoform. In addition, a neomycin resistance cassette was inserted downstream of exon 11. Translational activity of CELF1 is inhibited.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • CUGBP1-S302A,
  • CUGBP1-S302A
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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