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Allele : Rnaseh2a<tm1Crh> ribonuclease H2, large subunit; targeted mutation 1, Robert J Crouch

Primary Identifier  MGI:6147721 Allele Type  Targeted
Attribute String  Humanized sequence Gene  Rnaseh2a
Transmission  Germline Strain of Origin  C57BL/6N
Is Recombinase  false Is Wild Type  false
molecularNote  A serine substitution for glycine 37 (G37S) near the catalytic center on the RNase H2A subunit, a mutation associated with the human Aicardi-Goutieres syndrome, was introduced into this highly conserved residue of the catalytic subunit. A floxed selection cassette is present.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Rnaseh2a<G37S>,
  • Rnaseh2a<G37S>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele