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Allele : Spata16<em1Osb> spermatogenesis associated 16; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka U
Primary Identifier  MGI:6147689 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Spata16
Transmission  Germline Strain of Origin  (129S2/SvPas x C57BL/6NSlc)F1-Tg(CAG-EGFP,Acr-EGFP)2Osb
Is Recombinase  false Is Wild Type  false
description  EGR-G01 cells carry one copy of Tg(CAG-EGFP,Acr-EGFP)2Osb.
molecularNote  A point mutation (G to A) was introduced in codon 851 of exon 4, predicted to result in a R284Q alteration in the encoded protein. This mouse mutation corresponds to the single amino acid substitution (c.848G>A or R283Q) identified in infertile globozoospermic patients. RT-PCR analysis indicated that the point mutation caused no splicing abnormality.
  • mutations:
  • Single point mutation
  • synonyms:
  • Spata16<em1(R284Q)Osb)>,
  • Spata16<em1Maik>,
  • Spata16<em1(R284Q)Osb)>,
  • Spata16<pm>,
  • Spata16<pm>,
  • Spata16<em1Maik>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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