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Allele : Spata16<em2Osb> spermatogenesis associated 16; endonuclease-mediated mutation 2, Research Institute for Microbial Diseases, Osaka U

Primary Identifier  MGI:6147690 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Spata16
Transmission  Germline Strain of Origin  (129S2/SvPas x C57BL/6NSlc)F1-Tg(CAG-EGFP,Acr-EGFP)2Osb
Is Recombinase  false Is Wild Type  false
description  EGR-G01 cells carry one copy of Tg(CAG-EGFP,Acr-EGFP)2Osb.
molecularNote  CRISPR mutagenesis was used to generate a 781 bp deletion that removed 88 bp out of 90 bp of exon 4 which encodes the C-terminus of the tetratricopeptide repeat (TPR) domain. This deletion resulted in the mistranslation of the remaining 2 bp of the mutant fourth exon.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Spata16<-781>,
  • Spata16<-781>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories