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Allele : Map2k1<tm1(Map2k1,Map2k2)Chrn> mitogen-activated protein kinase kinase 1; targeted mutation 1, M Jean Charron

Primary Identifier  MGI:6148035 Allele Type  Targeted
Attribute String  Epitope tag, Inserted expressed sequence, Null/knockout Gene  Map2k1
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A cDNA of Map2k1 (tagged with Myc and flanked by loxP sites), an frt-flanked neomycin selection cassette, and a cDNA of Map2k2 were inserted into the first exon of Mek1. Western blot analysis showed that both endogenous Map2k1 protein and the Myc-tagged Map2k1 protein are expressed in heterozygous embryonic stem (ES) cells.
  • mutations:
  • Insertion
  • synonyms:
  • Mek1<1neo2>,
  • Mek1<1neo2>
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories