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Allele : Csn<em1Mam> casein gene family, alpha, beta, gamma, delta/epsilon, kappa; endonuclease-mediated mutation 1, Lothar Hennighausen

Primary Identifier	MGI:6148040	Allele Type	Endonuclease-mediated
Gene	Csn	Strain of Origin	C57BL/6NCrl
Is Recombinase	false	Is Wild Type	false

molecularNote

CRISPR-targeting removed 12 bp upstream of a CTCF binding site located between Sult1e1 and Csn1s1 as well as 44 bp downstream of the site, including 2 bp of the binding site.

mutations:
Intergenic deletion

earliestPublication:
Lee HK, et al. (2017) Functional assessment of CTCF sites at cytokine-sensing mammary enhancers using CRISPR/Cas9 gene editing in mice. Nucleic Acids Res 45(8):4606-4618

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

2 Publication categories

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