| Primary Identifier | MGI:6149757 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Arhgap21 |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by injecting Cas9 RNA and 4 guide sequences TGAGTGCTCTCAGAACCCAT, TTAGCCCACTGATTGTTGAG, TGTGGAGCTCAGACAGCAAC and GAGCAGTTTGATGTTTTAAA, which resulted in a 432 bp deletion beginning at Chromosome 2 position 20,889,665 bp and ending after 20,890,096 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001249954 (exon 5) and 353 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 126 and early truncation 8 amino acids later. |
