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Allele : Cflar<m1> CASP8 and FADD-like apoptosis regulator; mutation 1

Primary Identifier  MGI:6150920 Allele Type  Spontaneous
Attribute String  Modified isoform(s) Gene  Cflar
Strain of Origin  multiple strains Is Recombinase  false
Is Wild Type  false
molecularNote  This 21 bp insertion in the 3' UTR of exon 5 contains a putative binding site for the U2 snRNP that alters splicing. The insertion has been identified in MOLF/Ei, PWK/Ei and SPRETUS/Ei but not Mus musculus domesticus strains such as C57BL/6 or in CAST/EI. Hepatocytes from Mus musculus molossinus primarily express the long isoform whereas C57BL/6 hepatocytes express the short isoform.
  • mutations:
  • Insertion
  • synonyms:
  • Cflar<MSM>,
  • Cflar<MSM>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories