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Allele : Lmod3<em1(IMPC)Mbp> leiomodin 3 (fetal); endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis

Primary Identifier	MGI:6152507	Allele Type	Endonuclease-mediated
Attribute String	Null/knockout	Gene	Lmod3
Strain of Origin	C57BL/6NCrl	Is Recombinase	false
Is Wild Type	false	Project Collection	IMPC

molecularNote

This allele from IMPC was generated at UC Davis by injecting CAS9 Protein and 4 guide sequences GGTCAGCCTGAAACACATGGGGG, CCCTTGCCTAGCGCGCACAAAGC, GACTATAGCTCAGCTCATGTGGG, CCACCCTTGAGAGATTTTCTCAC, which resulted in a Whole-gene deletion.

mutations:
Intragenic deletion

earliestPublication:
Lastwika KJ, et al. (2016) Control of PD-L1 Expression by Oncogenic Activation of the AKT-mTOR Pathway in Non-Small Cell Lung Cancer. Cancer Res 76(2):227-38

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

5 Publication categories

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