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Allele : Cdc42ep3<em1(IMPC)Mbp> CDC42 effector protein 3; endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis

Primary Identifier	MGI:6152427	Allele Type	Endonuclease-mediated
Attribute String	Null/knockout	Gene	Cdc42ep3
Strain of Origin	C57BL/6NCrl	Is Recombinase	false
Is Wild Type	false	Project Collection	IMPC

molecularNote

This allele from IMPC was generated at UC Davis by injecting CAS9 Protein and 4 guide sequences GTGGCTCTAAAAACGAGACAGGG, CCACGCGGGTCTTTCCGGAGAGC, CCCAAATCCTGTAAGGTTGCTCG, CCTCTTAGACAGCCTGGATTTCT, which resulted in a Whole-gene deletion.

mutations:
Intragenic deletion

earliestPublication:
Adams DJ, et al. (2024) Genetic determinants of micronucleus formation in vivo. Nature 627(8002):130-136

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

5 Publication categories

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